| Viroptic (U.S.N.L.M.) | |
|---|---|
| Dosing/ HSV Keratitis | 1 drop q2hr while awake until complete re-epithelialization. Then 1 drop q4hr x 7 days. |
| Chem Specs | trifluridine 1.0% |
| Quantities | 7.5ml |
| Cost | 222.00 (generic) |
| Class | modified deoxyuridine, a nucleoside analogue |
| Action | replaces uracil, blocks base pairing |
| Activity |
Active against herpes simplex virus, types 1 and 2 and vacciniavirus. Some strains of adenovirus are also inhibited in vitro. |
| Indications |
Treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex virus, types 1 and 2. Treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex virus, types 1 and 2. |
| Keratoconjunctivitis dosing same as keratitis. | |
| Contraindications | Hypersensitivity to Viroptic or its components. |
| Pediatric use | >6 years |
| Pregnancy | Category C. There are no adequate studies in pregnant women. Fetal toxicity has been shown in animals at higher levels of exposure. Category C. There are no adequate studies in pregnant women. Fetal toxicity has been shown in animals at higher levels of exposure. |
| Consider Zirgan for more convenient dosing and less potential surface toxicity. Consider Zovirax (oral acyclovir) if expense is an issue or for long term prophylaxis. |