Restasis






          Restasis  (U.S.N.L.M.)
Dosing 1 drop bid 12 hours apart   (Shake emulsion)
Chem Specs cyclosporine 0.05%
Quantities 0.4 ml vials,  (30 or 60 vials per tray), and 5.5 ml in 10 ml bottle
Cost 366.00(box of 30 vials), 561.00 5.5ml bottle (Amazon)
Class peptide immunosuppressant
Action Calcineurin inhibitor, modulates T-cell function and increases goblet cell density.
Usage Indicated to increase tear production where tear production is presumed to be
suppressed due to ocular inflammation associated with keratoconjunctivitis sicca.
Increased tear production was not seen in patients concurrently taking topical anti-
inflammatory drugs or using punctal plugs.
Contraindications Active ocular infections and hypersensitivity to any ingredients in the formulation.
Pediatric use Safety and efficacy not established in pediatric patients below the age of 16.
Pregnancy Category C. Teratogenic in rats when administered at 5000x the normal human dose.
Can be used concomitantly with artificial tears, allowing 15 minutes between products.
Original Restasis patent ruled invalid. 0.09% Cequa and compounded 0.1% Klarity-C now available.
Canadian generic: www.mapleleafmeds.com $64.00/30 vials
    N.L.M. DailyMed page for Restasis          PDR page for Restasis