Phenylephrine






           Phenylephrine   (U.S.N.L.M.)
Dosing 1 or 2 drops of 2.5% or 10% every 3 to 5 minutes. Maximum of 3 drops per
eye. Use 2.5% for pediatric patients less than 1 year of age.
Chem Specs phenylephrine 2.5%, 10%
Quantities 10ml,15ml (2.5%).    5ml, (10%)
Cost 110.00/15ml
Class alpha-1 adrenergic receptor agonist
Action The α-adrenergic effect constricts the radial muscle of the iris and ophthalmic blood vessels
Usage Pupil dilation. Adjunctive IOP reduction.
Maximal mydriasis occurs in 20-90 minutes with recovery after 3 to 8 hours.
Contraindications Narrow angle glaucoma. 10% phenylephrine is contraindicated in patients with
hypertension, or thyrotoxicosis. 2.5% may be used with caution for these patients.
Pediatric use 10% phenylephrine is contraindicated in pediatric patients less than 1 year of age.
2.5% may be used with caution for these patients.
Pregnancy Category C. Fetal harm has been demonstrated in animal studies.
    N.L.M. DailyMed page for phenylephrine