| Amoxil (U.S.N.L.M.) | ||
|---|---|---|
| Dosing | Mild/Moderate: 250mg q8hr or 500mg q12hr. Severe: 500mg q8hr or 875mg q12hr. | |
| Chem Specs | amoxicillin | |
| Quantities | Tablets(500, 875mg), Capsul(250,500mg), Chewable(200, 400mg), Suspension(125, 200, 250, 400mg). |
|
| Cost | 12.12/30 generic | |
| Class | moderate-spectrum ß-lactam antibiotic (ampicillin analog) | |
| Action | ß-lactam antibiotics bind to transpeptidase (used by bacteria in cell wall synthesis). | |
| Usage | Indicated in the treatment of skin and skin structure infections due to ß-lactamase producing strains Streptococcus spp. (α- and ß-hemolytic strains only), Staphylococcus spp., or E. coli. |
|
| Susceptible to degradation by ß-lactamase-producing bacteria. Not useful for Pseudomonas aeruginosa. |
||
| Contraindications | Allergy to any of the penicillins. (Caution if history of cephalosporin allergy.) | |
| Pediatric use | Consult dosing tables (package insert ) and warnings for children under 40kg. | |
| Pregnancy | Category B. No evidence in rats of teratogenicity at 10x the human dose. | |
| Consider Septra (Monarch pharma) or Bactrim (Roche) when penicillin allergy is encountered. | ||